Nutritional Support for Detoxification
Fat soluble toxins are readily absorbed but poorly excreted, and therefore tend to accumulate in the body. To enable excretion, fat-soluble (lipophilic) chemicals are converted to water soluble substances through enzymatic conversion, referred to as Phase I and Phase II detoxification reactions, which occur in the liver and other tissues.
Phase I reactions are primarily "functionalization reactions", in which a functional group is added or exposed via oxidation, reduction of hydrolysis. Two enzyme systems are utilized for these reactions: the cytochrome P-450 monooxygenase system which is the predominant system, and the mixed-function amine oxidize system. Addition of a functional group allows the Phase I compound to undergo Phase II conjugation, although it may also be directly eliminated.
Phase II pathways are conjugation or synthetic reactions. Conjugation confers increased water solubility and the ability to undergo significant ionization at physiologic pH via covalent bonding of the foreign compound or intermediate to an endogenous molecule. The major conjugation reactions are glucuronidation, glutathione conjugation, amino acid conjugation, sulfating, acetylating and methylamine.
These two pathways may proceed separately and independently leading to the excretion of the modified xenophobic, or Phase I may produce an intermediate by adding or exposing a functional group which will then undergo Phase II conjugation. The Phase I intermediates can be highly reactive and are often more toxic than the parent compound. The enzymatic formation of an intermediate that is more toxic than the parent compound is referred to as bioactivation.
Two Capsules Contain:
Vitamin A 6665IU
(Natural Beta-Carotene w/Mixed Carotenoids, Palmitate)
Vitamin C (Magnesium Ascorbate) 167mg
Vitamin E 83IU
(as D-alpha Tocopherol Succinate)
Thiamine (HCI) 8.3mg
Riboflavin 8.3mg
(as Riboflavin-5 Phosphate)
Niacin 10mg
Vitamin B-6 (Pyridoxal-5'-Phosphate) 10mg
Folic Acid 200mcg
Vitamin B-12 (Cyanocobalamin) 41.6mcg
(as Cyanocobalamin, Adenosycobalamin)
Biotin 66.7mcg
Pantothenic Acid 33.3mg
(as Calcium Pantothenate)
Magnesium 78mg
(as Magnesium Citrate, Ascorbate, Malate)
Zinc (Picolinate) 10mg
Selenium (Seleno-L-Mehtionine) 66.7mcg
Copper (Sebicate) 66.7mcg
Manganese (Glycinate) 3.3mg
Molybdenum (Citrate) 50mcg
Calcium D-Glucarate 66.7mg
L-Methionine 66.7mg
Glycine 66.7mg
L-Glutamic Acid 66.7mg
Taurine 66.7mg
L-Glutamine 66.7mg
Choline (Bitartrate) 66.7mg
NAC (N-Acetyl Cysteine) 66.7mg
Quercetin 66.7mg
Inositol 33.3mg
L-Ornithine 33.3mg
Broccoli Aerial Parts Extract 33.3mg
(Brassica Oleracea)(0.7% Total Sulfur)
Milk Thistle Extract 16.7mg
(Silyburn Marianium)(80% Silymarin)
L-Glutathione 16.7mg
L-Serine 16.7mg
L-Histidine 16.7mg
L-Carnitine (Tartrate) 16.7mg
Coenzyme Q10 (Ubiquinone) 8.3mg
Proanthocyanidins 3.3mg
Superoxide Dismutase 33.3mcg
Catalase 16.7mcg
Other Ingredients: Maltodextrin, Magnesium Stearate, Vegetarian Capsules.
Contains No: Wheat, gluten, yeast, soy, animal or dairy products, artificial colors, sweeteners or preservatives.
Directions: Take one to three capsules twice daily between meals or as directed by a health care practitioner.
Warning: If you are pregnant or nursing consult your health care practitioner before use. Vitamin A intake in excessive amounts may be toxic and may increase the risk of birth defects. Pregnant women and those who may become pregnant should not exceed 5000 IU of pre-formed vitamin A (retinyl palmitate or retinyl acetate) per day. It is also recommended that children under four years of age avoid regurlarly consuming more than 2500 IU of pre-formed vitamin A per day.