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Abnormal purine and pyrimidine metabolism in autism: new uric acid test and related treatment for people with unique subtypes of autism and PDD.
by William Shaw, Ph.D.
Ted Page, Ph.D., and Mary Coleman, M.D., have established that abnormalities of purine and pyrimidine metabolism are common in children with autism and PDD. These abnormalities began to be reported over 30 years ago, but progress has been hampered because only a very small number of laboratories performed these tests and these laboratories were research laboratories that performed testing only on a very sporadic basis. The children with these genetic diseases have many or all of the classic symptoms of autism and therefore cannot easily be distinguished from “typical” children with autism. A critical finding of Drs. Page and Coleman is that two major subtypes of this disorder can be distinguished by a simple clinical test of urine, which is the content of uric acid.
Uric Acid Test
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