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Prealbumin (not to be confused with albumin) is an important marker for assessing protein deficiency. Prealbumin is produced in the liver, but is not affected by liver function unless function is extremely impaired. Biochemically, prealbumin has the function of transporting thyroid hormone. In addition, prealbumin also binds to retinol-binding protein (RBP), the main transport protein for free vitamin A.
In adults, prealbumin screening has been useful in assessing protein status in AIDS- or cancer-related cachexia, as well as nutritional status in nursing home residents.
In children, many parents have observed their children diagnosed with autism spectrum disorders showing symptoms of diarrhea, poor appetite or lack of weight gain, even if the child’s appetite is good. This test efficiently measures protein deficiency because prealbumin levels are not affected by hydration (fluid intake) or renal (kidney) function.
Prealbumin Test
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